General Hospital Preview: Friday, September 26, 2025 – A High-Stakes Battle for Monica’s Legacy Ignites
The drama is heating up on General Hospital this Friday, September 26, 2025, as secrets from the past collide with explosive confrontations in the present. With a powerful mix of amnesia, family revelations, and an inheritance dispute brewing, the stakes have never been higher. Here’s an in-depth look at the gripping storylines that will captivate fans this week.
Nathan’s Memory Mystery: The Lost Son Reawakens
At the heart of the episode is the enigmatic return of Nathan—who’s struggling to piece together his fractured memories. The revelation that Nathan suffers from amnesia and cannot recall events from the past seven years sets a tense emotional tone. His confused reaction to the news of his own survival stuns those around him, particularly Nina, who is quietly orchestrating the delicate process of informing Lisel Alrech, Nathan’s mother, that her son is still alive.
The dynamic between mother and son is fraught with emotional complexity. Lisel’s reaction is expected to be a mix of overwhelming relief and cautious hope, as Nathan’s memory recovery will be slow and fraught with setbacks. This storyline not only deepens the family drama but also ties into a larger mystery: the shadowy past involving FAC—a notorious figure with a chilling reputation.
FAC’s Shadow Looms Large: The Brain in the Jar Mystery
Anna’s investigation into Nathan’s situation takes a dark turn as suspicions arise that FAC might be behind the incident that led to Nathan’s amnesia. Known for his cunning ability to fake his own death, FAC remains an elusive and dangerous figure. Fans may recall the eerie image of FAC’s brain preserved in a jar years ago—a haunting visual that has fueled speculation about his continued influence.
Though FAC’s physical presence seems impossible, his legacy of sinister medical experimentation clearly lingers. Anna’s pursuit of the truth hints that FAC’s diabolical projects may still be active, threatening the safety and sanity of those caught in his web. This storyline promises to unearth new layers of intrigue and raise the stakes for Nathan and his allies.
Brit’s Emotional Reunion: A Sister’s Journey
Meanwhile, Brit receives life-altering news that her long-lost brother is alive—a revelation that sends her on a deeply emotional journey. Fans can anticipate a poignant reunion as Brit prepares to visit him, eager to bridge the years of separation and unravel the mysteries of their shared past.
Their conversation is expected to reveal hidden truths and spark emotional healing, adding depth to Brit’s character and exploring themes of family, forgiveness, and rediscovery. This subplot beautifully contrasts the darker threads of the episode, offering moments of warmth amid the tension.

Monica’s Memorial: Grief and Chaos Collide
The heart of the drama pulses around Monica’s memorial service, where emotions run high and old wounds are reopened. Brooklyn’s tearful goodbye to her mother Monica is a heartrending moment that captures the depth of loss felt by the Quartermaine family. Ned and Lys take on supportive roles, empathizing with their daughter’s pain and vowing to help Brooke Lynn navigate this difficult chapter.
Tracy’s eulogy is particularly poignant, revealing the profound impact Monica had on her life. Tracy’s admission that she’s uncertain if she can survive this pain underscores Monica’s irreplaceable role as a pillar in their lives.
Drew’s Controversial Arrival and the Battle Over Monica’s Will
Just when the memorial seems to offer a space for healing, chaos erupts with the unexpected arrival of Drew. His presence immediately stirs tension, as many mourners—especially Tracy and Michael—resent his intrusion. Drew insists on saying goodbye to Monica, but his true intentions quickly come into question.
In a dramatic twist, Drew announces he will read Monica’s last will in front of everyone, revealing an explosive claim: Monica left her entire estate to him. This revelation ignites a fierce battle over the inheritance, pitting Drew against Michael in a conflict filled with accusations, doubts, and high stakes.
Neither side is willing to back down. Tracy firmly believes Michael is the rightful heir, while Drew vehemently insists the legacy belongs to him. The tension is palpable as the fight for Monica’s fortune becomes a proxy for deeper family rivalries and unresolved tensions.
Monica’s Long-Lost Sister Emerges: A Shocking Will Reading
Just when the dispute seems at its peak, a new player enters the fray: Monica’s long-lost sister. The arrival of this unexpected relative promises to shake the foundations of the Quartermaine family. Portrayed by the formidable Erica Slezac, this character’s presence adds a fresh dynamic and a powerful voice in the unfolding battle.
Her declaration regarding Monica’s final wishes could upend everything, potentially validating or invalidating Drew’s shocking claims. Fans have eagerly awaited Erica’s return, and her role in this storyline is poised to deliver some of the most intense and dramatic moments in recent memory.
Michael and Willow’s Volatile Confrontation
In the midst of all the chaos, personal tensions flare as Michael confronts Willow once again. He sternly warns her to stay away from Drew’s manipulative grasp, particularly concerning Wy and Amelia. Michael’s message is clear: if Willow continues to allow Drew to control her life, she risks losing everything.
This heated exchange not only underscores the growing power struggle involving Drew but also highlights the personal costs borne by those caught in the crossfire. Michael’s protective instincts and unwavering determination add an emotional undercurrent to the episode’s broader narrative.
What’s Next for General Hospital?
Friday’s episode of General Hospital promises to be a rollercoaster of emotions, secrets, and power struggles. The unfolding mystery of Nathan’s amnesia and FAC’s shadowy influence, the poignant family reunions, and the fierce battle over Monica’s legacy combine to create a compelling and richly layered storyline.
As tensions escalate, alliances will be tested, and long-buried secrets will come to light—forcing each character to confront their past and fight for their future. For fans of the show, this episode is not to be missed, delivering the perfect blend of suspense, emotion, and explosive drama.
Stay tuned to General Hospital this Friday, September 26, 2025, for a landmark episode that will redefine family loyalties and leave viewers breathless.
